It's not possible to ignore activities from specific people to generate notifications, however, Winddle offers a feature to ignore activities coming either from all of your colleagues (internals) or all of your partners (externals). Additionally, it's also possible to mute all activities coming from automated process (usually, from external tools using Winddle API).
This feature is available from your user settings and will apply to all future activities.
Your profile icon in the top right corner > User settings > Notifications > Subscriptions : Mute your activity sources.
After updating, don't forget to save your changes by clicking on the button at the bottom of the page.